A small study at Yale demonstrated that treatment with naltrexone, an opioid-blocking agent used to treat alcohol use disorder, does not interfere with an antidepressant response to ketamine. Yoon, et al. followed 5 subjects being treated with naltrexone as they received ketamine infusions for depression. Three of five subjects showed remission, and 5/5 showed response. (See figure for details.)
This study contradicts an earlier one that showed no ketamine response for people under naltrexone blockage. More to come, I'm sure.
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